Article
Categorizing host-dependent RNA viruses by principal component analysis of their codon usage preferences.
Journal of computational biology : a journal of computational molecular cell biology - 1 Nov 2009
Su Ming-Wei, Lin Hsiu-Man, Yuan Hanna S, Chu Woei-Chyn
Abstract excerpt
Viruses have to exploit host transcription and translation mechanisms to replicate in a hostile host cellular environment, and therefore, it is likely that the infected host may impose pressure on viral evolution. In this study, we investigated differences in codon usage preferences among the highly mutable single strain RNA viruses which infect vertebrate or invertebrate hosts, respectively. We incorporate...
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