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Article

Metallothionein 1G promotes the differentiation of HT-29 human colorectal cancer cells

3 Apr 2017

Abstract excerpt

Metallothioneins (MTs) are a family of low-molecular-weight, cysteine-rich proteins involved in zinc and redox metabolism, that are epigenetically downregulated during colorectal cancer (CRC) progression, but may be re-induced with a variety of agents. Since loss of MT expression is associated with a worse prognosis, in the present study we investigated the effects of overexpression of the most significantly...

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PMID: 28393194
DOI: 10.3892/or.2017.5547

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