Article
Intergenotypic replacement of lyssavirus matrix proteins demonstrates the role of lyssavirus M proteins in intracellular virus accumulation.
Journal of virology - 1 Feb 2010
Finke Stefan, Granzow Harald, Hurst Jose, Pollin Reiko, Mettenleiter Thomas C
Abstract excerpt
Lyssavirus assembly depends on the matrix protein (M). We compared lyssavirus M proteins from different genotypes for their ability to support assembly and egress of genotype 1 rabies virus (RABV). Transcomplementation of M-deficient RABV with M from European bat lyssavirus (EBLV) types 1 and 2 r...
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