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Article

PPEY motif within the rabies virus (RV) matrix protein is essential for efficient virion release and RV pathogenicity.

Journal of virology - 1 Oct 2008

Wirblich Christoph, Tan Gene S, Papaneri Amy, Godlewski Peter J, Orenstein Jan Marc, Harty Ronald N, Schnell Matthias J

Abstract excerpt

Late (L) domains containing the highly conserved sequence PPXY were first described for retroviruses, and later research confirmed their conservation and importance for efficient budding of several negative-stranded RNA viruses. Rabies virus (RV), a member of the Rhabdoviridae family, contains the sequence PPEY (amino acids 35 to 38) within the N terminus of the matrix (M) protein, but the functions of this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Structure, Tertiary

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Identifiers

PMID: 18667490
DOI: 10.1128/JVI.00889-08
PMCID: PMC2546990

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