Identification and quantitative distribution of eight analogues of naturally occurring fecapentaenes in human feces by high-performance liquid chromatography.

doi:10.1093/carcin/12.2.199

Back to search

Article

Identification and quantitative distribution of eight analogues of naturally occurring fecapentaenes in human feces by high-performance liquid chromatography.

Carcinogenesis - 1 Feb 1991

de Kok T M, ten Hoor F, Kleinjans J C

Abstract excerpt

Fecapentaenes, highly potent fecal mutagens originating from intestinal bacterial production, have been suggested to play an essential role in the initiation of colorectal cancer. Reviewing the data on fecapentaene occurrence in man, the applied methodologies for fecapentaene extraction and analysis appear to be very inconsistent. Therefore, we compared several methods and developed an optimal extraction and...

Topics

Adult
Chromatography, High Pressure Liquid
Dose-Response Relationship, Drug
Drug Stability
Feces
Female
Genetic Variation
Humans
Male
Mutagenicity Tests
Mutagens

Polyenes

Salmonella

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Identification and quantitative distribution of eight analogues of naturally occurring fecapentaenes in human feces by high-performance liquid chromatography.PMID 1995185Read

Diet and Food chemicals increasing the risk of colorectal cancer – literature reviewSemantic proximity Read

Colon cancer risk factors from nutrition.Semantic proximity Read

A Comprehensive Overview of Colon Cancer- A Grim Reaper of the 21st CenturySemantic proximity Read

DIETARY FACTORS IN HUMAN COLORECTAL CANCERSemantic proximity Read

Factors Determining Colorectal Cancer: The Role of the Intestinal MicrobiotaSemantic proximity Read

Colorectal cancer chemoprevention--an overview of the science.Semantic proximity Read

Xenobiotics Formed during Food Processing: Their Relation with the Intestinal Microbiota and Colorectal CancerSemantic proximity Read

Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot studySemantic proximity Read