Article
An FM3A mutant, G258, with a mutation that affects both cell growth and oligosaccharide-lipid synthesis.
Biochimica et biophysica acta - 31 Jan 1991
Nishikawa Y
Abstract excerpt
I have previously isolated a temperature-sensitive FM3A mutant (G258) defective in asparagine-linked glycosylation. G258 shows not only the temperature sensitivity for cell growth, but also temperature sensitivity for synthesis of oligosaccharide-lipid (Nishikawa, Y. (1984) J. Cell. Physiol. 119, 260-266). In the present study, I isolated revertants for cell growth from G258 cells. All three growth revertants...
Topics
- Animals
- Asparagine
- Cell Division
- Cell Line
- Cell Survival
- Glycoproteins
- Glycosylation
- Mammary Neoplasms, Experimental
- Mice
- Mutation
- Oligosaccharides
- Temperature
