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Article

Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting.

Nature reviews. Drug discovery - 1 Dec 2009

Butler Georgina S, Overall Christopher M

Abstract excerpt

Proteomics has revealed that many proteins are present in unexpected cellular locations. Moreover, it is increasingly recognized that proteins can translocate between intracellular and extracellular compartments in non-conventional ways. This increases gene pleiotrophy as the diverse functions of...

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PMID: 19949400
DOI: 10.1038/nrd2945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19949400-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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