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Lineage and Host Source Are Both Correlated with Levels of Shiga Toxin 2 Production by <i>Escherichia coli</i> O157:H7 Strains

1 Dec 2009

Abstract excerpt

Escherichia coli O157:H7 strains fall into three major genetic lineages that differ in their distribution among humans and cattle. Several recent studies have reported differences in the expression of virulence factors between E. coli O157:H7 strains from these two host species. In this study, we wished to determine if important virulence-associated "mobile genetic elements" such as Shiga toxin 2 (Stx2)-encoding...

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PMID: 19948861
DOI: 10.1128/aem.01288-09

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