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The Shiga toxin 2 production level in enterohemorrhagic Escherichia coli O157:H7 is correlated with the subtypes of toxin-encoding phage.

Scientific reports - 16 Nov 2015

Ogura Yoshitoshi, Mondal Shakhinur Islam, Islam Md Rakibul, Mako Toshihiro, Arisawa Kokichi, Katsura Keisuke, Ooka Tadasuke, Gotoh Yasuhiro, Murase Kazunori, Ohnishi Makoto, Hayashi Tetsuya

Abstract excerpt

Enterohemorrhagic E. coli (EHEC) causes diarrhea and hemorrhagic colitis with life-threatening complications, such as hemolytic uremic syndrome. Their major virulence factor is Shiga toxin (Stx), which is encoded by bacteriophages. Of the two types of Stx, the production of Stx2, particularly that of Stx2a (a subtype of Stx2), is a major risk factor for severe EHEC infections, but the Stx2 production level is...

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Identifiers

PMID: 26567959
DOI: 10.1038/srep16663
PMCID: PMC4645166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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