Article
Up-regulation of TRPM6 transcriptional activity by AP-1 in renal epithelial cells.
Journal of cellular physiology - 1 Mar 2010
Ikari Akira, Sanada Ayumi, Okude Chiaki, Sawada Hayato, Yamazaki Yasuhiro, Sugatani Junko, Miwa Masao
Abstract excerpt
Transient receptor potential melastatin 6 (TRPM6) channel is involved in the reabsorption of magnesium in the kidney. We recently found that TRPM6 expression is up-regulated by EGF, but the regulatory mechanism has not been clear. TRPM6 mRNA was endogenously expressed in HEK293 cells. TRPM6 mRNA...
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