Article
A pH-responsive riboregulator.
Genes & development - 15 Nov 2009
Nechooshtan Gal, Elgrably-Weiss Maya, Sheaffer Abigail, Westhof Eric, Altuvia Shoshy
Abstract excerpt
The locus alx, which encodes a putative transporter, was discovered previously in a screen for genes induced under extreme alkaline conditions. Here we show that the RNA region preceding the alx ORF acts as a pH-responsive element, which, in response to high pH, leads to an increase in alx expression. Under normal growth conditions this RNA region forms a translationally inactive structure, but when exposed to...
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