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Human cytomegalovirus UL76 induces chromosome aberrations

25 Nov 2009

Abstract excerpt

BACKGROUND: Human cytomegalovirus (HCMV) is known to induce chromosome aberrations in infected cells, which can lead to congenital abnormalities in infected fetuses. HCMV UL76 belongs to a conserved protein family from herpesviruses. Some reported roles among UL76 family members include involvement in virulence determination, lytic replication, reactivation of latent virus, modulation of gene expression,...

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PMID: 19930723
DOI: 10.1186/1423-0127-16-107

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