Article
Characterisation of the proximal airway squamous metaplasia induced by chronic tobacco smoke exposure in spontaneously hypertensive rats.
Respiratory research - 24 Nov 2009
Bolton Sarah J, Pinnion Kate, Oreffo Victor, Foster Martyn, Pinkerton Kent E
Abstract excerpt
BACKGROUND: Continuous exposure to tobacco smoke (TS) is a key cause of chronic obstructive pulmonary disease (COPD), a complex multifactorial disease that is difficult to model in rodents. The spontaneously hypertensive (SH) rat exhibits several COPD-associated co-morbidities such as hypertensio...
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