Article
Genotyping in the cloud with Crossbow.
Current protocols in bioinformatics - 1 Sept 2012
Gurtowski James, Schatz Michael C, Langmead Ben
Abstract excerpt
Crossbow is a scalable, portable, and automatic cloud computing tool for identifying SNPs from high-coverage, short-read resequencing data. It is built on Apache Hadoop, an implementation of the MapReduce software framework. Hadoop allows Crossbow to distribute read alignment and SNP calling subtasks over a cluster of commodity computers. Two robust tools, Bowtie and SOAPsnp, implement the fundamental alignment...
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