Article
Cloud computing-based TagSNP selection algorithm for human genome data.
International journal of molecular sciences - 5 Jan 2015
Hung Che-Lun, Chen Wen-Pei, Hua Guan-Jie, Zheng Huiru, Tsai Suh-Jen Jane, Lin Yaw-Ling
Abstract excerpt
Single nucleotide polymorphisms (SNPs) play a fundamental role in human genetic variation and are used in medical diagnostics, phylogeny construction, and drug design. They provide the highest-resolution genetic fingerprint for identifying disease associations and human features. Haplotypes are regions of linked genetic variants that are closely spaced on the genome and tend to be inherited together. Genetics...
Topics
- Algorithms
- Computational Biology
- Genome, Human
- Genome-Wide Association Study
- Haplotypes
- Humans
- Linkage Disequilibrium
- Polymorphism, Single Nucleotide
