Article
Assessing the role of placental trisomy in preeclampsia and intrauterine growth restriction.
Prenatal diagnosis - 1 Jan 2010
Robinson Wendy P, Peñaherrera Maria S, Jiang Ruby, Avila Luana, Sloan Jennifer, McFadden Deborah E, Langlois Sylvie, von Dadelszen Peter
Abstract excerpt
OBJECTIVE: Prenatally diagnosed confined placental trisomy is associated with increased risk for intrauterine growth restriction (IUGR) and preeclampsia. However, it is unclear how often this might underlie pregnancy complications. Our objective was to evaluate the frequency and distribution of trisomic cells in placentae ascertained for IUGR and/or preeclampsia. METHOD: Comparative genomic hybridization was...
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