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Confined placental mosaicism: Distribution of chromosomally abnormal cells over the term placenta

15 Jun 2024

Abstract excerpt

OBJECTIVE: Non-invasive prenatal testing (NIPT) investigates placental DNA and may detect confined placental mosaicism (CPM). The aim of this study was to confirm CPM in the term placenta in cases with abnormal NIPT but normal follow-up cytogenetic studies of fetus and mother. Additionally we examined the distribution of abnormal cells over the placenta. METHODS: Four chorionic villus (CV) biopsies from four...

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PMID: 38901306
DOI: 10.1016/j.placenta.2024.06.008

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