Article
Telomerase deficiency and cancer susceptibility syndromes.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Nov 2009
Perona Rosario, Machado-Pinilla Rosario, Manguan Cristina, Carrillo Jaime
Abstract excerpt
Telomeres from most eukaryotes are composed of repeats of guanine-rich sequences whose main function is to preserve the end of the chromosomes. Telomeres are synthesised by a reverse transcriptase enzyme, telomerase (TERT), which forms part of a ribonucleoprotein complex containing also a RNA tem...
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