Article
Systemic properties of metabolic networks lead to an epistasis-based model for heterosis.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Jan 2010
Fiévet Julie B, Dillmann Christine, de Vienne Dominique
Abstract excerpt
The genetic and molecular approaches to heterosis usually do not rely on any model of the genotype-phenotype relationship. From the generalization of Kacser and Burns' biochemical model for dominance and epistasis to networks with several variable enzymes, we hypothesized that metabolic heterosis...
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