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Article

Monoamine oxidase A gene polymorphisms and enzyme activity associated with risk of gout in Taiwan aborigines.

Human genetics - 1 Feb 2010

Tu Hung-Pin, Ko Albert Min-Shan, Wang Shu-Jung, Lee Chien-Hung, Lea Rod A, Chiang Shang-Lun, Chiang Hung-Che, Wang Tsu-Nai, Huang Meng-Chuan, Ou Tsan-Teng, Lin Gau-Tyan, Ko Ying-Chin

Abstract excerpt

Taiwanese aborigines have a high prevalence of hyperuricemia and gout. Uric acid levels and urate excretion have correlated with dopamine-induced glomerular filtration response. MAOs represent one of the major renal dopamine metabolic pathways. We aimed to identify the monoamine oxidase A (MAOA, Xp11.3) gene variants and MAO-A enzyme activity associated with gout risk. This study was to investigate the...

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Identifiers

PMID: 19915868
DOI: 10.1007/s00439-009-0765-z

Genes

MAOA
COMT

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