Article
Caspase-6 activation in familial alzheimer disease brains carrying amyloid precursor protein or presenilin i or presenilin II mutations.
Journal of neuropathology and experimental neurology - 1 Dec 2009
Albrecht Steffen, Bogdanovic Nenad, Ghetti Bernardino, Winblad Bengt, LeBlanc Andréa C
Abstract excerpt
We previously demonstrated the activation of caspase-6 (Casp-6) in the hippocampus and cortex in cases of mild, moderate, severe, and very severe Alzheimer disease (AD). To determine whether Casp-6 is also activated in familial AD, we performed an immunohistochemical analysis of active Casp-6 and...
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