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Gly482Ser polymorphism in the peroxisome proliferator-activated receptor gamma coactivator-1alpha gene is associated with oxidative stress and abdominal obesity.

Metabolism: clinical and experimental - 1 Apr 2010

Weng Shao-Wen, Lin Tsu-Kung, Wang Pei-Wen, Chen I-Ya, Lee Hsin-Chen, Chen Shang-Der, Chuang Yao-Chung, Liou Chia-Wei

Abstract excerpt

The objective of the study was to o investigate the relationship of the Gly482Ser (G482S) polymorphism in the peroxisome proliferator-activated receptor gamma coactivator-1alpha (PPARGC1A) gene and type 2 diabetes mellitus (T2DM), obesity, and oxidative status in Chinese adults. We enrolled 276 T2DM patients and 1049 nondiabetic subjects aged at least 35 years. The G482S variant was detected using polymerase...

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PMID: 19913841
DOI: 10.1016/j.metabol.2009.08.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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