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Article

Characterization of an interleukin-6-mediated autocrine growth loop in the human multiple myeloma cell line, U266

1 Feb 1991

Abstract excerpt

It has been reported recently that freshly isolated human myeloma cell cultures proliferate in response to added interleukin-6 (IL-6). Endogenous levels of IL-6 found in the same cultures suggested that an autocrine growth loop may contribute to cell growth. However, the lack of homogenous cell populations in primary myeloma cultures has made it difficult to distinguish between paracrine and autocrine growth...

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Identifiers

PMID: 1991169
DOI: 10.1182/blood.v77.3.587.587

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Characterization of an interleukin-6-mediated autocrine growth loop in the human multiple myeloma cell line, U266PMID 1991169Read ↗

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