Article
A practical algorithm for estimation of the maximum likelihood ancestral reconstruction error.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2010
Hickey Glenn, Blanchette Mathieu
Abstract excerpt
The ancestral sequence reconstruction problem asks to predict the DNA or protein sequence of an ancestral species, given the sequences of extant species. Such reconstructions are fundamental to comparative genomics, as they provide information about extant genomes and the process of evolution tha...
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