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Article

A two-stage pruning algorithm for likelihood computation for a population tree.

Genetics - 1 Oct 2008

RoyChoudhury Arindam, Felsenstein Joseph, Thompson Elizabeth A

Abstract excerpt

We have developed a pruning algorithm for likelihood estimation of a tree of populations. This algorithm enables us to compute the likelihood for large trees. Thus, it gives an efficient way of obtaining the maximum-likelihood estimate (MLE) for a given tree topology. Our method utilizes the differences accumulated by random genetic drift in allele count data from single-nucleotide polymorphisms (SNPs), ignoring...

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Identifiers

PMID: 18780754
DOI: 10.1534/genetics.107.085753
PMCID: PMC2567359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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