Article
BslA, the S-layer adhesin of B. anthracis, is a virulence factor for anthrax pathogenesis.
Molecular microbiology - 1 Jan 2010
Kern Justin, Schneewind Olaf
Abstract excerpt
Microbial pathogens use adhesive surface proteins to bind to and interact with host tissues, events that are universal for the pathogenesis of infectious diseases. A surface adhesin of Bacillus anthracis, the causative agent of anthrax, required to mediate these steps has not been discovered. Previous work identified BslA, an S-layer protein, to be necessary and sufficient for adhesion of the anthrax vaccine...
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