Article
Galactosylation of the Secondary Cell Wall Polysaccharide of Bacillus anthracis and Its Contribution to Anthrax Pathogenesis.
Journal of bacteriology - 1 Mar 2018
Chateau Alice, Lunderberg Justin Mark, Oh So Young, Abshire Teresa, Friedlander Arthur, Quinn Conrad P, Missiakas Dominique M, Schneewind Olaf
Abstract excerpt
Bacillus anthracis, the causative agent of anthrax disease, elaborates a secondary cell wall polysaccharide (SCWP) that is essential for bacterial growth and cell division. B. anthracis SCWP is comprised of trisaccharide repeats with the structure, [→4)-β-ManNAc-(1→4)-β-GlcNAc(O3-α-Gal)-(1→6)-α-GlcNAc(O3-α-Gal, O4-β-Gal)-(1→]6-12 The genes whose products promote the galactosylation of B. anthracis SCWP are not...
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