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Article

A functional kinase homology domain is essential for the activity of photoreceptor guanylate cyclase 1.

The Journal of biological chemistry - 15 Jan 2010

Bereta Grzegorz, Wang Benlian, Kiser Philip D, Baehr Wolfgang, Jang Geeng-Fu, Palczewski Krzysztof

Abstract excerpt

Phototransduction is carried out by a signaling pathway that links photoactivation of visual pigments in retinal photoreceptor cells to a change in their membrane potential. Upon photoactivation, the second messenger of phototransduction, cyclic GMP, is rapidly degraded and must be replenished during the recovery phase of phototransduction by photoreceptor guanylate cyclases (GCs) GC1 (or GC-E) and GC2 (or GC-F)...

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Source

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Identifiers

PMID: 19901021
DOI: 10.1074/jbc.M109.061713
PMCID: PMC2804348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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