Article
White-matter markers for psychosis in a prospective ultra-high-risk cohort.
Psychological medicine - 1 Aug 2010
Bloemen O J N, de Koning M B, Schmitz N, Nieman D H, Becker H E, de Haan L, Dingemans P, Linszen D H, van Amelsvoort T A M J
Abstract excerpt
BACKGROUND: Subjects at 'ultra high risk' (UHR) for developing psychosis have differences in white matter (WM) compared with healthy controls. WM integrity has not yet been investigated in UHR subjects in relation to the development of subsequent psychosis. Hence, we investigated a prospective cohort of UHR subjects comparing whole brain fractional anisotropy (FA) of those later developing psychosis (UHR-P) to...
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