Article
Using genetic, cognitive and multi-modal neuroimaging data to identify ultra-high-risk and first-episode psychosis at the individual level.
Psychological medicine - 1 Dec 2013
Pettersson-Yeo W, Benetti S, Marquand A F, Dell'acqua F, Williams S C R, Allen P, Prata D, McGuire P, Mechelli A
Abstract excerpt
BACKGROUND: Group-level results suggest that relative to healthy controls (HCs), ultra-high-risk (UHR) and first-episode psychosis (FEP) subjects show alterations in neuroanatomy, neurofunction and cognition that may be mediated genetically. It is unclear, however, whether these groups can be differentiated at single-subject level, for instance using the machine learning analysis support vector machine (SVM)....
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