Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Major contribution of dominant inheritance to autism spectrum disorders (ASDs) in population-based families.

Journal of human genetics - 1 Dec 2009

Nishiyama Takeshi, Notohara Morihiro, Sumi Satoshi, Takami Satoshi, Kishino Hirohisa

Abstract excerpt

Results of twin studies have shown that autism spectrum disorders (ASDs) are attributable to complex multigenic interactions rather than to a single susceptibility gene. However, the growing number of distinct, individually rare genetic causes of ASDs, mostly copy number variations (CNVs), favors an alternative to the polygenic hypothesis, the two-component model, which suggests that ASDs are caused either by de...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Child Development Disorders, Pervasive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Family Health

Share to Genes, Dominant

Share to Infant

Share to Models, Genetic

Share to Siblings

Source

Identifiers

PMID: 19893580
DOI: 10.1038/jhg.2009.105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Major contribution of dominant inheritance to autism spectrum disorders (ASDs) in population-based families.PMID 19893580Read ↗

How rare and common risk variation jointly affect liability for autism spectrum disorder.Semantic proximity Read ↗

The contributions of rare inherited and polygenic risk to ASD in multiplex families.Semantic proximity Read ↗

Exploring the common genetic architecture of autism spectrum disorder using a novel multi-polygenic risk score approachSemantic proximity Read ↗

The Familial Risk of Autism Spectrum Disorder with and without Intellectual Disability.Semantic proximity Read ↗

Using large clinical data sets to infer pathogenicity for rare copy number variants in autism cohorts.Semantic proximity Read ↗

Rare Inherited and De Novo CNVs Reveal Complex Contributions to ASD Risk in Multiplex Families.Semantic proximity Read ↗

A unified genetic theory for sporadic and inherited autism.Semantic proximity Read ↗

The penetrance of copy number variations for schizophrenia and developmental delay.Semantic proximity Read ↗

Most genetic risk for autism resides with common variation.Semantic proximity Read ↗

Common genetic risk factors in ASD and ADHD co-occurring familiesSemantic proximity Read ↗

Do common variants play a role in risk for autism? Evidence and theoretical musings.Semantic proximity Read ↗

The familial co-aggregation of ASD and ADHD: a register-based cohort study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.