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Article

NinaB is essential for Drosophila vision but induces retinal degeneration in opsin-deficient photoreceptors.

The Journal of biological chemistry - 15 Jan 2010

Voolstra Olaf, Oberhauser Vitus, Sumser Emerich, Meyer Nina E, Maguire Michael E, Huber Armin, von Lintig Johannes

Abstract excerpt

In animals, visual pigments are essential for photoreceptor function and survival. These G-protein-coupled receptors consist of a protein moiety (opsin) and a covalently bound 11-cis-retinylidene chromophore. The chromophore is derived from dietary carotenoids by oxidative cleavage and trans-to-cis isomerization of double bonds. In vertebrates, the necessary chemical transformations are catalyzed by two distinct...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19889630
DOI: 10.1074/jbc.M109.056101
PMCID: PMC2804369

Genes

RPE65

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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