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Article

Leishmaniacell surface prohibitin: role in host-parasite interaction

2 Nov 2009

Abstract excerpt

Proteins selectively upregulated in infective parasitic forms could be critical for disease pathogenesis. A mammalian prohibitin orthologue is upregulated in infective metacyclic promastigotes of Leishmania donovani, a parasite that causes visceral leishmaniasis. Leishmania donovani prohibitin shares 41% similarity with mammalian prohibitin and 95-100% within the genus. Prohibitin is concentrated at the surface...

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PMID: 19888987
DOI: 10.1111/j.1462-5822.2009.01406.x

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