Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors.

Oncology reports - 1 Dec 2009

Davis Rachel, Singh Karan P, Kurzrock Razelle, Shankar Sharmila

Abstract excerpt

Recent studies have suggested that sulforaphane, a compound found largely in cruciferous vegetables, could inhibit tumor growth through regulation of angiogenesis. However, the molecular mechanism by which it inhibits angiogenesis has not been reported. In this study, we examined the molecular mechanisms by which sulforaphane (SNF) inhibits angiogenesis through regulation of FOXO transcription factor in human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis Inhibitors
Share to Anticarcinogenic Agents
Share to Endothelium, Vascular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Box Protein O1

Share to Forkhead Transcription Factors

Share to Isothiocyanates

Share to Neovascularization, Pathologic

Share to Proto-Oncogene Proteins c-akt

Source

Identifiers

PMID: 19885601
DOI: 10.3892/or_00000589

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors.PMID 19885601Read ↗

Role of FOXO Transcription Factors in Cancer Metabolism and AngiogenesisSemantic proximity Read ↗

Sulforaphane Causes Cell Cycle Arrest and Apoptosis in Human Glioblastoma U87MG and U373MG Cell Lines under Hypoxic ConditionsSemantic proximity Read ↗

Flavonoids with Anti-Angiogenesis Function in CancerSemantic proximity Read ↗

Inactivation of AKT, ERK and NF-κB by genistein derivative, 7-difluoromethoxyl-5,4′-di-n-octylygenistein, reduces ovarian carcinoma oncogenicitySemantic proximity Read ↗

The angiogenic effects of Angelica sinensis extract on HUVEC in vitro and zebrafish in vivo.Semantic proximity Read ↗

Mechanistic Insights into 2-5(H)-Furanone-Mediated Inhibition of Angiogenesis Using HUVECs and Zebrafish ModelsSemantic proximity Read ↗

Modulation of markers associated with aggressive phenotype in MDA-MB-231 breast carcinoma cells by sulforaphane.Semantic proximity Read ↗

Bufalin suppresses tumour microenvironment-mediated angiogenesis by inhibiting the STAT3 signaling pathwaySemantic proximity Read ↗

Fisetin inhibits various attributes of angiogenesis in vitro and in vivo--implications for angiopreventionSemantic proximity Read ↗

Quercetin Synergistically Potentiates the Anti-Angiogenic Effect of 5- Fluorouracil on HUVEC Cell LineSemantic proximity Read ↗

AKT/NF‐κB inhibitor xanthohumol targets cell growth and angiogenesis in hematologic malignanciesSemantic proximity Read ↗

Sulforaphane inhibits growth of phenotypically different breast cancer cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.