Article
Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster.
PLoS biology - 1 Nov 2009
Goetze Sandra, Qeli Ermir, Mosimann Christian, Staes An, Gerrits Bertran, Roschitzki Bernd, Mohanty Sonali, Niederer Eva M, Laczko Endre, Timmerman Evy, Lange Vinzenz, Hafen Ernst, Aebersold Ruedi, Vandekerckhove Joël, Basler Konrad, Ahrens Christian H, Gevaert Kris, Brunner Erich
Abstract excerpt
Protein modifications play a major role for most biological processes in living organisms. Amino-terminal acetylation of proteins is a common modification found throughout the tree of life: the N-terminus of a nascent polypeptide chain becomes co-translationally acetylated, often after the removal of the initiating methionine residue. While the enzymes and protein complexes involved in these processes have been...
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