Article
A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo.
Blood - 7 Jan 2010
Li Keguo, Blum Yannick, Verma Anjali, Liu Zhong, Pramanik Kallal, Leigh Noah R, Chun Chang Z, Samant Ganesh V, Zhao Baofeng, Garnaas Maija K, Horswill Mark A, Stanhope Stephen A, North Paula E, Miao Robert Q, Wilkinson George A, Affolter Markus, Ramchandran Ramani
Abstract excerpt
Recently, messenger RNAs in eukaryotes have shown to associate with antisense (AS) transcript partners that are often referred to as long noncoding RNAs (lncRNAs) whose function is largely unknown. Here, we have identified a natural AS transcript for tyrosine kinase containing immunoglobulin and epidermal growth factor homology domain-1 (tie-1), tie-1AS lncRNA in zebrafish, mouse, and humans. In embryonic...
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