Article
Purification of an equine apotransferrin variant (thyromedin) essential for thyroid hormone dependent growth of GH1 rat pituitary tumor cells in chemically defined culture.
Biochemistry - 8 Jan 1991
Sirbasku D A, Stewart B H, Pakala R, Eby J E, Sato H, Roscoe J M
Abstract excerpt
Pituitary tumor cells require thyroid hormones for growth in vivo [Sorrentino, J. M., Kirkland, W. L., & Sirbasku, D. A. (1976) J. Natl. Cancer Inst. 56, 1155-1158]. In vitro, GH1 rat pituitary tumor cells were studied in a serum-free defined medium (PCM-10) formulated with Ham's F12 and Dulbecco...
Topics
- Amino Acid Sequence
- Animals
- Apoproteins
- Cell Division
- Cell Line
- Chromatography, Affinity
- Chromatography, Ion Exchange
- Culture Media
- Electrophoresis, Polyacrylamide Gel
- Genetic Variation
- Horses
- Kinetics
- Molecular Sequence Data
- Molecular Weight
- Pituitary Neoplasms