Article
Effects of injury and insulin on lipid synthesis from glucose by the rat thoracic aorta.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jan 2000
Capron L, Jarnet J
Abstract excerpt
Chronic hyperinsulinemia is suspected of enhancing the development of arterial diseases. However, direct metabolic effects of insulin on the inner arterial wall are poorly documented. To assess the possible influence of variations in smooth muscle phenotype, we measured lipogenesis from glucose by rat thoracic aortas that had been injured with a balloon catheter. Aortas were exposed to insulin during either a...
Topics
- Animals
- Aorta, Thoracic
- DNA
- Dose-Response Relationship, Drug
- Glucose
- Insulin
- Lipids
- Male
- Muscle, Smooth, Vascular
- Phenotype
- Rats
- Rats, Inbred Strains
