Article
Coordination of gene expression with growth rate: a feedback or a feed-forward strategy?
FEBS letters - 17 Dec 2009
Levy Sagi, Barkai Naama
Abstract excerpt
In the budding yeast, a large fraction of genes is coordinately regulated with growth rate. We argue that this correlation does not reflect a direct feedback from growth rate to gene expression. Rather, what appears to be a response to growth rate is dominated by environmental sensing. External parameters, such as nutrition or temperature, feed-forward to define gene expression pattern that is tuned to the...
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