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Article

Genetic evidence for pax-3 function in myogenesis in the nematode Pristionchus pacificus.

Evolution & development - 1 Jan 2000

Yi Buqing, Bumbarger Dan, Sommer Ralf J

Abstract excerpt

PAX3 is a member of the PAX3/7 subfamily of the paired box proteins. In vertebrates, Pax3 is essential for skeletal myogenesis by activating a cascade of transcriptional events that are necessary and sufficient for skeletal myogenesis. Four related basic helix-loop-helix transcription factors, MyoD, Myf5, Mrf4, and Myogenin, are targets of PAX3 and serve as myogenic regulatory factors. Although the role of Pax3...

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Source

Identifiers

PMID: 19878288
DOI: 10.1111/j.1525-142X.2009.00374.x

Genes

PAX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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