Article
Mannitol challenge for assessment of airway responsiveness, airway inflammation and inflammatory phenotype in asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Feb 2010
Wood L G, Powell H, Gibson P G
Abstract excerpt
BACKGROUND: Assessment of airway inflammation in asthma is becoming increasingly important, as the inflammatory phenotype underpins the treatment response. OBJECTIVE: This study aimed to evaluate mannitol as a tool for assessing airway responsiveness and airway inflammation in asthma, compared with hypertonic saline. METHODS: Fifty-five subjects with stable asthma completed a hypertonic (4.5%) saline challenge...
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