Article
Laterality defects other than situs inversus totalis in primary ciliary dyskinesia: insights into situs ambiguus and heterotaxy.
Chest - 1 Nov 2014
Shapiro Adam J, Davis Stephanie D, Ferkol Thomas, Dell Sharon D, Rosenfeld Margaret, Olivier Kenneth N, Sagel Scott D, Milla Carlos, Zariwala Maimoona A, Wolf Whitney, Carson Johnny L, Hazucha Milan J, Burns Kimberlie, Robinson Blair, Knowles Michael R, Leigh Margaret W
Abstract excerpt
BACKGROUND: Motile cilia dysfunction causes primary ciliary dyskinesia (PCD), situs inversus totalis (SI), and a spectrum of laterality defects, yet the prevalence of laterality defects other than SI in PCD has not been prospectively studied. METHODS: In this prospective study, participants with suspected PCD were referred to our multisite consortium. We measured nasal nitric oxide (nNO) level, examined cilia...
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