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Characterisation of a new infectious full-length cDNA clone of BVDV genotype 2 and generation of virus mutants.

Veterinary microbiology - 21 Apr 2010

Mischkale Katrin, Reimann Ilona, Zemke J, König P, Beer Martin

Abstract excerpt

Based on their genomic sequences, two genotypes of Bovine viral diarrhea virus (BVDV) can be differentiated, BVDV type 1 (BVDV-1) and BVDV type 2 (BVDV-2). The complete genomic sequence of the highly virulent BVDV-2 strain 890 was cloned as cDNA to establish the infectious cDNA clone p890FL. In vitro-synthesised full-length RNA of p890FL was transfected into bovine cells and infectious virus could be recovered...

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Identifiers

PMID: 19875251
DOI: 10.1016/j.vetmic.2009.09.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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