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Article

Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility.

FEBS letters - 3 May 2010

Hakomori Sen-itiroh

Abstract excerpt

Glycosphingolipids (GSLs) GM3 (NeuAcalpha3Galbeta4Glcbeta1Cer) and GM2 (GalNAcbeta4[NeuAcalpha3]Galbeta4Glcbeta1Cer) inhibit (i) cell growth through inhibition of tyrosine kinase associated with growth factor receptor (GFR), (ii) cell adhesion/motility through inhibition of integrin-dependent signaling via Src kinases, or (iii) both cell growth and motility by blocking "cross-talk" between integrins and GFRs....

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Identifiers

PMID: 19874824
DOI: 10.1016/j.febslet.2009.10.065
PMCID: PMC2867360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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