Article
T-cell subsets with a naive phenotype are selectively decreased in the peripheral blood of patients with mycosis fungoides.
The Journal of investigative dermatology - 1 Jan 1991
Gilmore S J, Benson E M, Kelly J W
Abstract excerpt
Peripheral blood lymphocytes of 33 patients with histopathologic confirmation of mycosis fungoides and 27 healthy controls matched for age and sex were analyzed with a panel of monoclonal antibodies using both single and dual color immunofluorescence. Patients with mycosis fungoides had a significant reduction in the percentage of circulating T cells with a naive phenotype (i.e., CD4+2H4+ and CD4+Leu8+), as well...
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