Article
Mycosis fungoides exhibits a Th1-type cell-mediated cytokine profile whereas Sezary syndrome expresses a Th2-type profile.
The Journal of investigative dermatology - 1 Jul 1994
Saed G, Fivenson D P, Naidu Y, Nickoloff B J
Abstract excerpt
We determined T-cell cytokine profiles in the epidermis, dermis, and blood of cutaneous T-cell lymphoma to differentiate whether unique cytokine profiles were associated with mycosis fungoides (MF) versus Sezary syndrome. Punch biopsy specimens from plaque stage MF (n = 7) were compared to Sezary...
Topics
- Base Sequence
- Biopsy
- Blotting, Southern
- Cytokines
- DNA, Neoplasm
- Diagnosis, Differential
- Gene Expression Regulation, Neoplastic
- Humans
- Immunity, Cellular
- Interferon-gamma
- Interleukin-10
- Interleukin-2
- Interleukin-4
- Interleukin-5
- Molecular Sequence Data
- Mycosis Fungoides
- Phenotype
- Polymerase Chain Reaction