Functional consequences of substitution of the active site (phospho)histidine residue of Escherichia coli succinyl-CoA synthetase.

doi:10.1016/0167-4838(91)90223-m

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Article

Functional consequences of substitution of the active site (phospho)histidine residue of Escherichia coli succinyl-CoA synthetase.

Biochimica et biophysica acta - 8 Jan 1991

Majumdar R, Guest J R, Bridger W A

Abstract excerpt

Succinyl-CoA synthetase (EC 6.2.1.5, succinate:CoA ligase (ADP-forming] of Escherichia coli is an alpha 2 beta 2 tetramer, with the active site believed to be located at the point of contact between the two subunit types. It has been previously established that the reaction involves the intermedi...

Topics

Adenosine Diphosphate
Adenosine Triphosphate
Binding Sites
Electrophoresis, Polyacrylamide Gel
Escherichia coli
Gene Expression
Histidine
Kinetics
Mutation
Phosphorylation
Succinate-CoA Ligases

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