Article
Interleukin-1 beta single-nucleotide polymorphism's C allele is associated with elevated risk of gastric cancer in Helicobacter pylori-infected Peruvians.
The American journal of tropical medicine and hygiene - 1 Nov 2009
Gehmert Sebastian, Velapatiño Billie, Herrera Phabiola, Balqui Jaqueline, Santivañez Livia, Cok Jaime, Vargas Gloria, Combe Juan, Passaro Douglas J, Wen Sijin, Meyer Frank, Berg Douglas E, Gilman Robert H
Abstract excerpt
Particular alleles of the interleukin-1B (IL-1B) gene have been correlated with increased risk of atrophic gastritis and gastric cancer in the populations of East Asia and Europe. No such data exist from Peru, a developing country with a population genotypically different from others studied and with a high prevalence of Helicobacter pylori infection and gastric cancer. We conducted a case-control study comparing...
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