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Article

Characterization of the functional role of nucleotides within the URE2 IRES element and the requirements for eIF2A-mediated repression.

RNA (New York, N.Y.) - 1 Dec 2009

Reineke Lucas C, Merrick William C

Abstract excerpt

Cap-independent initiation of translation is thought to promote protein synthesis on some mRNAs during times when cap-dependent initiation is down-regulated. However, the mechanism of cap-independent initiation is poorly understood. We have previously reported the secondary structure within the yeast minimal URE2 IRES element. In this study, we sought to investigate the mechanism of internal initiation in yeast...

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Share to Eukaryotic Initiation Factor-2
Share to Glutathione Peroxidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nucleotides

Share to Poly A

Share to Prions

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Share to Regulatory Elements, Transcriptional

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Source

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Identifiers

PMID: 19861427
DOI: 10.1261/rna.1722809
PMCID: PMC2779687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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