Analysis of isoniazid and rifampicin resistance in Mycobacterium tuberculosis isolates in Morocco using GenoType® MTBDRplus assay.

doi:10.1016/j.jgar.2017.09.017

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Article

Analysis of isoniazid and rifampicin resistance in Mycobacterium tuberculosis isolates in Morocco using GenoType® MTBDRplus assay.

Journal of global antimicrobial resistance - 1 Mar 2018

Ennassiri Wifak, Jaouhari Sanae, Sabouni Radia, Cherki Wafa, Charof Reda, Filali-Maltouf Abdelkarim, Lahlou Ouafae

Abstract excerpt

OBJECTIVES: The number of multidrug-resistant tuberculosis (MDR-TB) cases is rising worldwide. The present investigation aimed to evaluate, using the GenoType® MTBDRplus assay, the most common mutations associated with rifampicin (RIF) and isoniazid (INH) resistance among resistant strains in Morocco. METHODS: A total of 319 Mycobacterium tuberculosis isolates sent to the National Tuberculosis Reference...

Topics

Adult
Antitubercular Agents
Bacterial Proteins
Bacterial Typing Techniques
Drug Resistance, Multiple, Bacterial
Female
Genotype
Humans
Isoniazid
Male
Microbial Sensitivity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Morocco

Mutation

Mycobacterium tuberculosis

Rifampin

Tuberculosis, Multidrug-Resistant

Young Adult

Source

Open in PubMed

Identifiers

PMID: 28993300
DOI: 10.1016/j.jgar.2017.09.017

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